Protein Details: Calcium release-activated calcium channel protein 1

Protein ID

ICDB_Pro_1753

Protein Name

Calcium release-activated calcium channel protein 1

Gene Name

ORAI1 CRACM1 TMEM142A RCJMB04_8f15

Organism

Gallus gallus (Chicken)

Length

226 amino acids

AlphaFoldDB

AF-Q5ZL05-F1-model_v4.pdb

Function

Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores.

Sequence

MSLNEHSMQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDAEHDYPRGLLIAFSACTTVLVAVHLFALMISTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFSTVIGTLLFLAEVVLLCWVKFLPLKKNPLDPAENSNSSITSGQAAAIASTSIMVPFGLIFIVFAVHFYRSLVSHKTDRQFQELNELAEFAWLQDQLDHRGDAISPAVTHFA

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

DOI ID

10.1186/gb-2004-6-1-r6

RefSeq

NP_001025829.1